Case Western Reserve University
Researchers make discovery in colon cancer prevention
Published in Women's Health Weekly, June 4th, 2009
A new study finds that individuals who have low expression of the "Celebrex gene," 15-PGDH, are actually resistant to Celebrex treatment when used to prevent colon cancer. The study, published in this week's issue of the Proceedings of the National Academy of Sciences (PNAS), is by Sanford Markowitz, M.D., Ph.D., the Markowitz-Ingalls Professor of Cancer Genetics at the Case Western Reserve University School of Medicine and an oncologist at the Ireland Cancer Center of University Hospitals Case Medical Center and his colleagues.
"These findings have two important practical implications," said Markowitz, who is also an investigator in the Howard Hughes Medical Institute....
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