Women's Health Weekly
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Breast Cancer
Studies from University of Insubria provide new data on breast cancer
June 4th, 2009
"In the Milan area (Northern Italy), we identified a family characterized by a high prevalence of ovarian and breast cancer cases (5 out of 6 subjects, over 3 generations), and a predominant prevalence of ovarian lesions (4 out of 5 patients). Analysis of BRCA1 and BRCA2 genes allowed the identification of the missense c.190T >C mutation in codon 64 (Cys64Arg) of BRCA1," investigators in Varese, Italy report. "The aims of the present investigation were to characterize the functional implications of the c.190T >C mutation at the molecular level, and to search whether additional polymorphisms might be linked to the peculiar phenotypic features observed in the...
Source: Women's Health Weekly (2009-06-04)
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