Women's Health Weekly
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Breast Cancer
Data on breast cancer described by F. Li et al
June 11th, 2009
According to recent research published in the journal Clinical Oncology, "Cyclooxygenase-2 (COX-2) is involved in carcinogenesis, immune response suppression, apoptosis inhibition, angiogenesis, and tumour cell invasion and metastasis. The gene for COX-2, designated as PTGS2, carries several polymorphisms, such as -765G > C, 1195G/A in the promoter region, and 8473T > C in the 3' UTR, which have been associated with susceptibility to malignant disease." "The aim of this study was to search for new mutations and polymorphisms in the COX-2 gene and to assess the relationship with breast cancer. In the present study, we identified a novel single nucleotide...
Source: Women's Health Weekly (2009-06-11)
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