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Women's Health Weekly

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Breast Cancer



Findings from University of Texas advance knowledge in breast cancer



June 11th, 2009

According to a study from the United States, "The ubiquitously expressed 14-3-3 proteins are involved in numerous important cellular functions. The loss of 14-3-3 sigma is a common event in breast cancer; however, the role of other 14-3-3s in breast cancer is unclear."

"Recently, we found that 14-3-3 zeta overexpression occurs in early stage breast diseases and contributes to transformation of human mammary epithelial cells. Here, we show that 14-3-3 zeta overexpression also persisted in invasive ductal carcinoma and contributed to the further progression of breast cancer. To examine the clinical effect of 14-3-3 zeta overexpression in advanced stage breast cancer, we...


Source: Women's Health Weekly (2009-06-11)

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