Women's Health Weekly
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Breast Cancer
Investigators at Fudan University target breast cancer
June 11th, 2009
"The proper interaction between BRIP1/BACH1 and BRCA1 protein has been found to be crucial for BRCA1-mediated DNA double-strand break repair and BRIP1/BACH1 mutations were estimated to confer a relative risk for breast cancer of 2.0 in western populations. In Chinese population, BRCA1 mutations could explain a relatively large proportion of inherited breast cancer cases in comparison with BRCA2 mutations, which probably deduced a hypothesis that those genes involved in BRCA1-mediated DNA repair pathway might play a more significant role in the etiology of Chinese breast cancer," investigators in Shanghai, People's Republic of China report. "To investigate the...
Source: Women's Health Weekly (2009-06-11)
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