Women's Health Weekly
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Breast Cancer
Investigators at Southern Illinois University zero in on breast cancer
June 11th, 2009
"The function of Ca2+ and the calcium sensing receptor (CaSR) in breast epithelium and its relationship to mammary carcinogenesis is poorly understood. In this study, we determined the function of this ligand receptor system in regulating the biologic properties of the estrogen receptor-positive MCF-7 and the estrogen receptor-negative MDA-MB-435 human breast cancer cells," scientists in the United States report. "Physiologic concentration of extracellular Ca2+, (by comparison to cells cultured in control low Call medium) down-modulated cellular proliferation, cellular invasion and growth in soft agarose in both of these cell lines. Physiologic concentration of...
Source: Women's Health Weekly (2009-06-11)
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