Ovarian Cancer

New research on ovarian cancer from Catholic University summarized

Published in Women's Health Weekly, June 11th, 2009

According to recent research from Campobasso, Italy, "Epithelial ovarian cancer is the leading cause of gynecological cancer mortality. Despite good response to surgery and initial chemotherapy, chemoresistance occurrence represents a major obstacle to a successful therapy."

"To better understand biological mechanisms at the basis of paclitaxel resistance, a comparative proteomic approach based on DIGE coupled with mass spectrometry (MALDI-TOF and LC-MS/MS) was applied to the human epithelial ovarian cancer cell lines A2780 and its paclitaxel resistant counterpart A2780TC1. Most of the differentially expressed proteins between the two cell lines belong to the class of...

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Source: Women's Health Weekly (2009-06-11)

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