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Women's Health Weekly

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Breast Cancer



Report summarizes breast cancer study findings from C.J. Cheng and co-researchers



June 11th, 2009

"Signal peptide-CUB-epidermal growth factor-like domain-containing protein 2 (SCUBE2), originally identified from the endothelium and several nonendothelial primary cell types, was recently shown to be expressed in invasive breast carcinomas. However, the protein localization and biological significance of SCUBE2 in breast cancer are unknown," scientists writing in the journal Cancer Research report.

"In this report, we show by anti-SCUBE2 immunostaining that SCUBE2 is mainly expressed in vascular endothelial and mammary ductal epithelial cells in normal breast tissue. In addition, we observed positive staining for SCUBE2 in 55% (86 of 156) of primary breast...


Source: Women's Health Weekly (2009-06-11)

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