Women's Health Weekly
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Breast Cancer
Researchers' work from Osaka University, Medical Department focuses on breast cancer
June 11th, 2009
"Accurate assessment of metastasis in sentinel lymph nodes (SLN) of breast cancer is important but involves a heavy workload for the pathologist. We conducted a multicenter clinical trial in Japan to evaluate a new automated assay system for cytokeratin 19 mRNA, the one-step nucleic acid amplification (OSNA) assay (Sysmex), to detect lymph node metastasis of breast cancer," scientists writing in the journal Clinical Cancer Research report. "Surgically obtained axillary lymph nodes were sectioned into four pieces, two of which were examined with the OSNA assay. The other two adjacent pieces were examined with H&E and immunohistochemical staining for cytokeratin...
Source: Women's Health Weekly (2009-06-11)
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