Women's Health Weekly
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Breast Cancer
Studies from M.P. Santiago and co-researchers yield new data on breast cancer
June 11th, 2009
"Trastuzumab has substantially changed the prognosis of breast carcinomas. As HER2 over-expression/amplification is a prerequisite for treatment with trastuzumab, an accurate assessment of HER-2 status is the first step for successful treatment," scientists in Spain report. "In metastatic breast cancer, we routinely assess HER2 expression in the primary tumour, assuming that HER2 status remains stable through cancer progression. However, it is frequent to find reports that describe discordance between HER2 expression in primary and metastatic tumours. The aim of this paper was to verify whether HER2 status of breast carcinomas is maintained in the corresponding axillary...
Source: Women's Health Weekly (2009-06-11)
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