Drug Resistance

New drug resistance data have been reported by scientists at Fudan University

Published in Women's Health Weekly, June 11th, 2009

According to recent research from Shanghai, People's Republic of China, "Besides its therapeutic effects, chemotherapeutic agents also enhance the malignancy of treated cancers in clinical situations. Recently, epithelia I-mesenchymal transition (EMT) has attracted attention in studies of tumor progression."

"We aimed to test whether transient Adriamycin treatment induces EMT and apoptosis simultaneously in cancer cells, clarify why the same type of cells responds differentially (i.e., apoptosis, EMT) to Adriamycin treatment, and elucidate the role of Twist1, the master regulator of EMT, in this process. In unsynchronized MCF7 cells or cells synchronized at different...

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Source: Women's Health Weekly (2009-06-11)

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