Myeloproliferative Disorders

New data from Shinshu University, Medical Department illuminate research in myeloproliferative disorders

Published in Women's Health Weekly, June 18th, 2009

According to a study from Matsumoto, Japan, "We report a male infant with Down syndrome who had a transient myeloproliferative disorder associated with skin lesions. He was transferred to a neonatal intensive care Unit because of low body weight, fetal edema, disseminated intravascular coagulation, and 10% blast cells in the peripheral blood."

"On postnatal day (ID) 1, erythema with small papules, vesicles, and Pustules appeared on the entire body. A smear preparation from the pustules on PD 2 showed 10% blast cells. A biopsy specimen taken on PD 5 revealed subcorneal pustules containing neutrophils and eosinophils. Genetic analyses detected a somatic mutation (197G...

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Source: Women's Health Weekly (2009-06-18)

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