Women's Health Weekly
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Breast Cancer
Reports outline breast cancer study results from Thomas Jefferson University
June 18th, 2009
According to recent research from the United States, "The (HER2/Neu) ErbB2 oncogene is commonly over-expressed in human breast cancer and is sufficient for mammary tumorigenesis in transgenic mice. Nuclear factor (NF)-kappa B activity is increased in both human and murine breast tumors." "The immune response to mammary tumorigenesis may regulate tumor progression. The role of endogenous mammary epithelial cell NF-kappa B had not previously been determined in immune-competent animals. Furthermore, the role of the NF-kappa B components, p50 and p65, in tumor growth was not known. Herein, the expression of a stabilized form of the NF-kappa B-inhibiting I kappa B alpha...
Source: Women's Health Weekly (2009-06-18)
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