Women's Health Weekly
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Breast Cancer
Studies from R. Castellocros and co-researchers in the area of breast cancer published
June 18th, 2009
According to recent research published in the journal BMC Cancer, "Interactions between cancer cells and stroma are critical for growth and invasiveness of epithelial tumors. The biochemical mechanisms behind tumor-stromal interactions leading to increased invasiveness and metastasis are mostly unknown." "The goal of this study was to analyze the direct effects of staged stroma-derived extracellular matrices on breast cancer cell behavior. Early and late three-dimensional matrices were produced by NIH-3T3 and tumor-associated murine fibroblasts, respectively. After removing fibroblasts, extracted matrices were re-cultured with breast epithelial cells of assorted...
Source: Women's Health Weekly (2009-06-18)
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