Women's Health Weekly
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Breast Cancer
Studies from S.P. Pitroda and colleagues reveal new findings on breast cancer
June 18th, 2009
"The mucin 1 (MUC1) oncoprotein is aberrantly overexpressed in human breast cancers. Although MUC1 modulates the activity of estrogen receptor alpha (ER), there is no information regarding the effects of MUC1 on global gene expression patterns and the potential role of MUC1-induced genes in predicting outcome for breast cancer patients," scientists writing in the journal Proceedings of the National Academy of Sciences of the United States of America report. "We have developed an experimental model of MUC1-induced transformation that has identified the activation of genes involved in cholesterol and fatty acid metabolism. A 38-gene set of experimentally derived...
Source: Women's Health Weekly (2009-06-18)
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