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Women's Health Weekly

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Breast Cancer



Studies from University of Sao Paulo, Medical Department further understanding of breast cancer



June 18th, 2009

According to recent research published in the journal BMC Cancer, "HER-2 gene testing has become an integral part of breast cancer patient diagnosis. The most commonly used assay in the clinical setting for evaluating HER-2 status is immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH)."

"These procedures permit correlation between HER-2 expression and morphological features. However, FISH signals are labile and fade over time, making post-revision of the tumor difficult. CISH (chromogenic in situ hybridization) is an alternative procedure, with certain advantages, although still limited as a diagnostic tool in breast carcinomas. To elucidate...


Source: Women's Health Weekly (2009-06-18)

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