Women's Health Weekly
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Cancer
New cancer study findings have been reported by A. Zollner and co-researchers
June 18th, 2009
"Overexpression of human CYP4Z1, a cytochrome P450 enzyme, has been correlated with poor prognosis in human cancer," scientists in Saarbrucken, Germany report. "However, its catalytic properties are not yet known. We expressed this P450 in Schizosaccharomyces pombe and demonstrate by whole-cell biotransformation assays CYP4Z1-dependent in-chain hydroxylation of lauric and myristic acid, which in both cases leads to the formation of four different monohydroxylated products at positions omega-2, omega-3, omega-4, and omega-5, respectively," wrote A. Zollner and colleagues. The researchers concluded: "The CYP4Z1-expressing fission yeast should be a new...
Source: Women's Health Weekly (2009-06-18)
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