Women's Health Weekly
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Breast Cancer
Data from Dongeui University provide new insights into breast cancer
June 25th, 2009
"Tight junctions (TJs) are critical structures for the maintenance of cellular polarity, acting as paracellular permeability barriers and playing an essential role in regulation of the diffusion of fluid, electrolytes and macromolecules through the paracellular pathway. Matrix metalloproteinases (MMPs) have been implicated as possible mediators of invasiveness and metastasis in some cancers," scientists writing in the journal Chemico - Biological Interactions report. "In this study, it was investigated the effect of sanguinarine, a benzophenanthridine alkaloid, on the correlation between the tightening of TJs and the anti-invasive activity in human breast...
Source: Women's Health Weekly (2009-06-25)
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