Women's Health Weekly
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Breast Cancer
Research findings from University of Helsinki update understanding of breast cancer
June 25th, 2009
In this recent study, researchers in Helsinki, Finland conducted a study "To determine the effect of the breast cancer susceptibility mutation PALB2 1592delT on tumor phenotype and patient survival. We defined the PALB2 mutation status in 947 familial and 1,274 sporadic breast cancer patients and 1,079 population controls, and compared tumor characteristics and survival in mutation carriers relative to other familial and sporadic cases and to 79 BRCA1 and 104 BRCA2 mutation carrier cases." "The PALB2 1592delT mutation was found in 19 familial [2.0%; odds ratio, 11.03; 95% confidence interval (95% Cl), 2.65-97.78; P< 0.0001] and eight sporadic patients (0.6%; odds...
Source: Women's Health Weekly (2009-06-25)
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