Women's Health Weekly
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Breast Cancer
Research from U.H. Weidle et al broadens understanding of breast cancer
June 25th, 2009
According to recent research from Penzberg, Germany, "The gene encoding CRASH, a human asparaginase-like protein, has been cloned and its transcriptional activation has been detected in gynecologic cancers. To define the expression of CRASH in human tumors and its possible functional role, monoclonal antibodies against the CRASH protein have been. generated." "In non-transformed tissues CRASH was only, detected in testis, brain, esophagus, prostate and proliferating endometrium. On the other hand, 36150 ovarian carcinomas, 16178 mammary carcinomas, 616 uroepithelial bladder carcinomas and 5133 colon carcinomas scored positive for CRASH, with the absence of reactivity in...
Source: Women's Health Weekly (2009-06-25)
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