Women's Health Weekly
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Breast Cancer
Researchers at University of Adelaide release new data on breast cancer
June 25th, 2009
According to recent research published in the journal Cell Death and Differentiation, "Chemokine receptors are essential mediators of the metastatic spread in various cancer types; however their precise function in the development of secondary tumors remains poorly understood. We report here a novel property of the chemokine receptors CXCR4 and CCR7 in inhibiting detachment-induced cell death - anoikis, which is believed to be one of the major blocks in the metastatic spread of various neoplasms." "Activation of these chemokine receptors by their respective ligands, CXCL12 and CCL21 specifically reduced the sensitivity of metastatic breast cancer cells to anoikis...
Source: Women's Health Weekly (2009-06-25)
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