Women's Health Weekly
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Cancer
Data on cancer detailed by H.J. Thirkettle and co-authors
June 25th, 2009
"LYRIC/AEG-1 has been reported to influence breast cancer survival and metastases, and its altered expression has been found in a number of cancers. The cellular function of LYRIC/AEG-1 has previously been related to its subcellular distribution in cell lines," scientists in Cambridge, the United Kingdom report. "LYRIC/AEG-1 contains three uncharacterized nuclear localization signals (NLS), which may regulate its distribution and, ultimately, function in cells. Immunohistochemistry of a human prostate tissue microarray composed of 179 prostate cancer and 24 benign samples was used to assess LYRIC/AEG-1 distribution. Green fluorescent protein-NLS fusion proteins and...
Source: Women's Health Weekly (2009-06-25)
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