Women's Health Weekly
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Fox Chase Cancer Center
'Disordered' amino acids may really be there to provide wiggle room for signaling protein
June 25th, 2009
Sections of proteins previously thought to be disordered may in fact have an unexpected biological role – providing certain proteins room to move -- according to a study published by researchers at Fox Chase Cancer Center in this month's issue of the journal Structure (Cell Press). The researchers published the first comprehensive structural study of the protein NHERF1, which serves as a means of bringing together molecular signals between the outer membrane of a cell and the proteins found in the structures that form the cell's cytoskeleton. NHERF1 is representative of a large class of proteins with an array of biological roles, including signaling pathways implicated...
Source: Women's Health Weekly (2009-06-25)
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