Women's Health Weekly
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Breast Cancer
Investigators at Tufts University, Medical Department release new data on breast cancer
July 2nd, 2009
According to a study from the United States, "Breast cancer development is a complex pathobiological process involving sequential genetic alterations in normal epithelial cells that results in uncontrolled growth in a permissive microenvironment. Accordingly, physiologically relevant models of human breast cancer that recapitulate these events are needed to study cancer biology and evaluate therapeutic agents." "Here, we report the generation and utilization of the human breast cancer in mouse (HIM) model, which is composed of genetically engineered primary human breast epithelial organoids and activated human breast stromal cells. By using this approach, we have...
Source: Women's Health Weekly (2009-07-02)
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