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Women's Health Weekly

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Breast Cancer



Recent findings from A.P. Araujo and co-authors highlight research in breast cancer



July 2nd, 2009

"Growth factors are important mediators of proliferation. Deregulation in growth factor mechanisms as well as in its receptors will contribute to cancer development," scientists in Oporto, Portugal report.

"One of the most important is the epidermal growth factor (EGF), which is encoded by EGF gene. A functional polymorphism at position 61 (A/G) is associated with increased expression of EGF. Thus, we proposed to assess genotype frequencies in a case-control study and appraise their association to breast cancer risk. Using the polymerase chain reaction technique combined with restriction enzyme fragment length polymorphism (PCR-RFLP) we analyzed DNA from 883 women (500...


Source: Women's Health Weekly (2009-07-02)

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