Urinary Tract Infection
Studies from University of Maryland, Medical Department describe new findings in urinary tract infection
Published in Women's Health Weekly, July 2nd, 2009
"Capsule expression may be important during ascending Escherichia coli urinary tract infections (UTIs). An isogenic ksl(k2) ABCDE mutant of extraintestinal pathogenic E. coli (ExPEC) strain CFT073 that could not synthesize the K2 capsule was compared with wild-type CFT073, to determine virulence in a murine model of ascending UTI and in vitro killing assays," investigators in the United States report.
"No significant differences were observed regarding the abilities of the mutant and the wild-type CFT073 strains to colonize the murine urinary tract in single-challenge infection experiments. However, in competitive-colonization experiments, the mutant was significantly...
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