Women's Health Weekly
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Cancer
Research data from Peking University update understanding of cancer
July 2nd, 2009
"In the present study, we incorporated docetaxel (DTX) into an injectable thermo-sensitive mixed micelle gel (MMG). It was found that the mixed micelle composed Of Pluronic F127 (PF127) and Tween 80 overcame the problem of PF127 micelle on physical stability and drug release due to the low solubilization capacity of PF127 for the high lipophility of DTX molecules," researchers in Beijing, People's Republic of China report. "Then, DTX MMG was characterized in vitro and in vivo, compared with DTX PF127 gel and free DTX. The sulforhodamine B (SRB) staining assay in both human breast cancer MCF-7 and ovarian cancer SKOV-3 cell lines revealed that DTX loaded mixed micelles...
Source: Women's Health Weekly (2009-07-02)
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