Women's Health Weekly
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Breast Cancer
New breast cancer data have been reported by J. Maltavacas and co-authors
July 9th, 2009
According to recent research from Lisbon, Portugal, "It is now widely recognized that translation factors are involved in cancer development and that components of the translation machinery that are deregulated in cancer cells may become targets for cancer therapy. The eukaryotic Release Factor 3 (eRF3) is a GTPase that associates with eRF1 in a complex that mediates translation termination. eRF3a/GSPT1 first exon contains a (GGC)n expansion coding for proteins with different N-terminal extremities." "Herein we show that the longer allele (12-GGC) is present in 5.1% (7/137) of the breast cancer patients analysed and is absent in the control population (0/135),...
Source: Women's Health Weekly (2009-07-09)
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