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Women's Health Weekly

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Breast Cancer



New findings from M. Jager and co-researchers in the area of breast cancer described



July 9th, 2009

According to recent research from Munich, Germany, "Human epidermal growth factor receptor 2 (HER2/neu) is an important target for the treatment of the breast cancers in which it is overexpressed. However, no approved anti-HER2/neu therapy is available for the majority of breast. cancer patients, who express HER2/neu at low levels (with scores of 1+ or 2+/fluorescence in situ hybridization-negative)."

"The trifunctional antibody ertumaxomab targets HER2/neu, CD3, and activating Fc gamma receptors. In presence of ertumaxomab, tri-cell complexes consisting of tumor cells, T cells, and accessory cells form to cause tumor cell lysis. In it phase I trial with metastatic...


Source: Women's Health Weekly (2009-07-09)

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