Women's Health Weekly
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Breast Cancer
Research on breast cancer published by M.S. Denzel et al
July 9th, 2009
"High levels of the fat-secreted cytokine adiponectin (APN) are present in the circulation of healthy people, whereas low levels correlate with an increased incidence of breast cancer in women. The current study experimentally probes the physiologic functions of APN in mammary cancer in a newly generated genetic mouse model," scientists writing in the journal Clinical Cancer Research report. "We established an APN null mouse model of mammary cancer by introducing the polyoma virus middle T (PyV-mT) oncogene expressed from mouse mammary tumor virus (MMTV) regulatory elements into APN null mice. MMTV-PyV-mT-induced tumors resemble ErbB2-amplified human breast...
Source: Women's Health Weekly (2009-07-09)
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