Women's Health Weekly
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Research
New mechanism for amyloid beta protein's toxic impact on the Alzheimer's brain
July 9th, 2009
Scientists have uncovered a novel mechanism linking soluble amyloid protein with the synaptic injury and memory loss associated with Alzheimer's disease (AD). The research, published by Cell Press in the June 25 issue of the journal Neuron, provides critical new insight into disease pathogenesis and reveals signaling molecules that may serve as potential additional therapeutic targets for AD. Amyloid protein (A) plays a major pathogenic role in AD, a devastating neurodegenerative disorder characterized by progressive cognitive impairment and memory loss. "Given the mounting evidence that small soluble A assemblies mediate synaptic impairment in AD, elucidating the...
Source: Women's Health Weekly (2009-07-09)
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