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Autoimmune Disease

Research from University of Michigan, Rheumatology Division provide new insights into autoimmune disease

Published in Women's Health Weekly, August 6th, 2009

Researchers detail in 'Stronger inflammatory/cytotoxic T-cell response in women identified by microarray analysis,' new data in autoimmune disease. According to a study from the United States, "Women develop chronic inflammatory autoimmune diseases more often than men. The mechanisms causing the increased susceptibility are incompletely understood."

"Chronic immune stimulation characterizes many autoimmune disorders. We hypothesized that repeated stimulation may cause a different T-cell response in women than in men. Microarrays were used to compare gene expression in T cells from healthy men and women with and without repeated stimulation. Four days after a single...

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