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Ovarian Cancer

Research from H. Chen and co-researchers yields new findings on ovarian cancer

Published in Women's Health Weekly, August 13th, 2009

A new study, 'Coexpression of invasive markers (uPA, CD44) and multiple drug-resistance proteins (MDR1, MRP2) is correlated with epithelial ovarian cancer progression,' is now available. According to recent research from Henan, People's Republic of China, "Invasion and metastases of cancer cells and the development of resistance to anticancer therapies are the main causes of treatment failure and mortality in cancer patients. We evaluated invasive markers of urokinase plasminogen activator (uPA) and CD44 and multiple drug-resistance (MDR) markers of MDR1 and MRP2 in four epithelial ovarian cancer (EOC) cell lines, primary tumours (n=120) and matched metastatic lesions (n=40) by...

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