Published in Women's Health Weekly, September 3rd, 2009
"Physiological conditions of moderate hypoxia in breast cancer also activate another transcription factor, hypoxia-inducible factor-1 alpha (HIF-1 alpha). In addition, the transcription factors p53 and the estrogen receptor alpha (ER alpha) are important key players in breast cancer progression. Here, human breast cancer cells cultured under mild hypoxic conditions were exposed to TCDD and analyzed for regulation of p53...
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