B-Cell Lymphoma

Investigators at University of Helsinki target B-cell lymphoma

Published in Women's Health Weekly, September 24th, 2009

According to a study from Helsinki, Finland, "Maspin is a serine protease inhibitor with tumor suppressor activity. Maspin can suppress tumor growth and metastasis in vivo and turner cell motility and invasion in vitro."

"Maspin also modulates apoptosis Of tumor cells, possibly by modulating the expression of the B-cell lymphoma-2 family member. p53 regulates the expression of the tumor suppressor gene maspin. Breast cancer is known for its propensity to recur even after decades. The biology behind this phenomenon of tumor dormancy is poorly understood. This study was conducted to clarify the role of maspin and B-cell lymphoma-2 in early and late recurring breast...

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Source: Women's Health Weekly (2009-09-24)

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