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Breast Cancer

Research by M.E. Platek and colleagues in breast cancer provides new insights

Published in Women's Health Weekly, October 29th, 2009

"It has been hypothesized that effects of alcohol consumption on one-carbon metabolism may explain, in part, the association of alcohol consumption with breast cancer risk. The methylenetetrahydrofolate reductase (MTHFR) and 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR) genes express key enzymes in this pathway," scientists in the United States report.

"We investigated the association of polymorphisms in MTHFR (rs1801133 and rs1801131) and MTR (rs1805087) with breast cancer risk and their interaction with alcohol consumption in a case-control study-the Western New York Exposures and Breast Cancer study. (n = 1,063) were women with primary, incident...

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