Breast Cancer
Research from W. Zwart et al has provided new information about breast cancer
Published in Women's Health Weekly, October 29th, 2009
"Arzoxifene is an effective growth inhibitor of ER alpha-positive breast cancer cells, including tamoxifen-resistant tumors. In this study, we show that overexpression of a regular component of the ER alpha transcription factor complex, cyclin D1, which occurs in approximately 40% of breast cancer patients, renders cells resistant to the new promising antiestrogen, arzoxifene. Overexpression of cyclin D1 alters the...
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