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Women's Health Weekly

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Apoptosis



Research from W. Chaouki and co-authors yields new data on apoptosis



November 5th, 2009

"Many natural components of plants extract are studied for their beneficial effects on health and particularly on carcinogenesis chemoprevention. In this study, we investigated the effect of citral (3,7-dimethyl-2,6-octadienal), a key component of essential oils extracted from several herbal plants, on the proliferation rate, cell cycle distribution, and apoptosis of the human breast cancer cell line MCF-7," scientists in Morocco report.

"The effects of this compound were also tested on cyclo-oxygenase activity. Citral treatment caused inhibition of MCF-7 cell growth (IC50-48 h: 18 x 10(-5) m), with a cycle arrest in G(2)/M phase and apoptosis induction. Moreover, we...


Source: Women's Health Weekly (2009-11-05)

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