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Spontaneous Abortion

Research on spontaneous abortion published by scientists at University Hospital

Published in Women's Health Weekly, November 19th, 2009

According to a study from Louvain, Belgium, "About 50% of spontaneous abortions are caused by fetal chromosome abnormalities. Identification of these abnormalities helps to estimate recurrence risks in future pregnancies."

"However, due to Culture failures or maternal contamination often no fetal karyotype can be obtained. Array comparative genomic hybridization can overcome some of these limitations. In this study, we analyzed 103 miscarriages by both T-banding and 1-Mb array comparative genomic hybridization. We found an overall abnormality rate of 35% (34 of 96). In a comparison of 70 samples that were successfully analyzed by both techniques, 54 (77%) had identical...

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