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Hormones

Research from University of Virginia in the area of hormones described

Published in Women's Health Weekly, November 26th, 2009

According to a study from the United States, "Subsequent to suppression of LH (GnRH) pulse frequency by progesterone (P) and estradiol (E-2), LH pulse frequency remains slow for 7 days after P withdrawal if mid-luteal E-2 concentrations are maintained. This may reflect an ability of E-2 to potentiate the suppressive effects of low P levels."

"We explored this notion in a similar experimental paradigm by administering a P-receptor antagonist (mifepristone) after P withdrawal while continuing E-2. Studies were performed in seven ovulatory, non-obese women. Transdermal E-2 (0.2 mg/day) and oral micronized P (100 mg every 8 h) were started within 24 h of the LH surge and...

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