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Cancer Gene Therapy

Recent findings from Z.Y. Chen and co-authors highlight research in cancer gene therapy

Published in Women's Health Weekly, December 17th, 2009

"Survivin is an attractive target for tumor growth inhibition and represents a significant approach to anticancer therapy. RNA interference is an important tool for specifically down-regulating the expression of cellular genes," scientists in Guangzhou, People's Republic of China report.

"However, the efficiency of short hairpin RNA (shRNA) on the expression of survivin gene and the influence on the cell apoptosis transfected by the non-viral gene transfer system of ultrasound-targeted microbubble destruction was not explored. In this work, recombinant expression plasmid of shRNA targeting survivin gene was constructed and added to cultured cervical cancer cells...

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