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Breast Cancer

Reports outline breast cancer research from C. Wong and colleagues

Published in Women's Health Weekly, December 31st, 2009

According to a study from the United States, "Aromatase inhibitors are important drugs to treat estrogen receptor a (ER alpha)-positive postmenopausal breast cancer patients. However, development of resistance to aromatase inhibitors has been observed."

"We examined whether the heat shock protein 90 (HSP90) inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG) can inhibit the growth of aromatase inhibitor-resistant breast cancers and the mechanisms by which 17-DMAG affects proliferation. Aromatase inhibitor-responsive MCF-7aro and aromatase inhibitor-resistant LTEDaro breast epithelial cells were used in this study. We observed that 17-DMAG inhibited...

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