Angiogenesis

Study data from X.L. Du and colleagues update understanding of angiogenesis

Published in Women's Health Weekly, January 14th, 2010

"Osteopontin (OPN) has been found to play an important role in tumor angiogenesis in recent years. Our previous studies have shown that OPN is overexpressed in tumor-associated human endometrial endothelial cells (HEECs) isolated from tissue samples of patients with endometrial cancer," scientists in Jinan, People's Republic of China report.

"In the present study, we aimed to further determine the role of OPN in endometrial cancer-associated angiogenesis. We knock down OPN expression in HEECs and human endometrial cancer Ishikawa (ISK) cells using the small interference RNA method, and then evaluate the effects of OPN oil endometrial cancer-associated angiogenesis by in...

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Source: Women's Health Weekly (2010-01-14)

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