Gastric Cancer

Research reports from China Medical University provide new insights into gastric cancer

Published in Women's Health Weekly, February 18th, 2010

According to recent research from Taichung, Taiwan, "Exonuclease 1 (Exo1) is an important nuclease involved in the mismatch repair system that contributes to the maintenance of genomic stability, modulation of DNA recombination and mediation of cell cycle arrest. Potential polymorphisms in Exo1 may alter cancer risks by influencing the repair activity of Exo1."

"We hypothesized that single-nucleotide poly in orph isms (SNPs) in Exo1 might be associated with risks of gastric cancer. In this hospital-based study, the association of Exo1 A-1419G (rs3754093), C-908G (rs10802996), A238G (rs1776177), C498T (rs1635517), K589E (rs1047840), G670E (rs1776148), C723R (rs1635498),...

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Source: Women's Health Weekly (2010-02-18)

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