Apoptosis Therapy
Studies from C. Palacios and co-authors have provided new information about apoptosis therapy
Published in Women's Health Weekly, February 25th, 2010
A report, 'Down-regulation of RIP expression by 17-dimethylaminoethylamino-17-demethoxygeldanamycin promotes TRAIL-induced apoptosis in breast tumor cells,' is newly published data in Cancer Letters. "The Hsp90 inhibitor 17DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin) is undergoing clinical trials as an antitumor drug. We show here that treatment of human breast cancer cells with 17DMAG facilitates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis," investigators in Sevilla, Spain report.
"Down-regulation of receptor interacting protein (RIP1) is observed upon 17DMAG treatment concomitantly with inhibition of...
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