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Breast Cancer

Research from Cornell University yields new data on breast cancer

Published in Women's Health Weekly, March 11th, 2010

Scientists discuss in 'EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation' new findings in breast cancer. According to recent research from the United States, "EGF receptor (EGFR) signaling in human cancers elicits changes in protein-expression patterns that are crucial for potentiating tumor growth. Identifying those proteins with expression regulated by the EGFR and determining how they contribute to malignancy is fundamental for the development of more effective strategies to treat cancer."

"Here, we show that tissue transglutaminase (tTG) is one such protein. EGF up-regulates tTG expression in human...

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