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Journal of the National Cancer Institute

News brief: Poorer breast cancer survival associated with micrometastases in axillary lymph nodes

Published in Women's Health Weekly, March 18th, 2010

Metastases that were 2 millimeters or less in diameter ("micrometastases") in axillary lymph nodes detected on examination of a single section of the lymph nodes were associated with poorer disease-free and overall survival in breast cancer patients, according to a new study published online February 26 in the Journal of the National Cancer Institute.

The prognostic relevance of isolated tumor cells and micrometastases in lymph nodes in breast cancer patients has become a major issue since the introduction of the sentinel lymph node procedure. Recently, patients with minimal lymph node involvement detected after a sentinel node procedure in the Dutch MIRROR study were...

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