Breast Cancer
Study data from Northwestern University, Department of Surgery provide new insights into breast cancer
Published in Women's Health Weekly, March 25th, 2010
Fresh data on breast cancer are presented in the report 'Reevaluating cathepsin D as a biomarker for breast cancer: serum activity levels versus histopathology.' According to recent research published in the journal Cancer Biology & Therapy, "Cathepsin D is a lysosomal hydrolase involved in intra-and extracellular proteolysis. This enzyme is aberrantly produced and processed in malignancy, and most notably is over-secreted into the tumor cell microenvironment."
"This hyper-secretion may lead to excessive degradation of the extracellular matrix, and contribute to tumor progression and metastases. These phenomena have been established in vitro, and there is...
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