Ovarian Cancer

Studies from Nagoya University, Medical Department have provided new information about ovarian cancer

Published in Women's Health Weekly, March 25th, 2010

According to a study from Nagoya, Japan, "Dipeptidyl peptidase IV (DPPIV/CD26) is a multifunctional cell surface aminopeptidase that is widely expressed in different cell types. Recent studies have suggested that DPPIV plays an important role in tumor progression in several human malignancies."

"In the current study, we investigated the role of DPPIV in paclitaxel resistance in epithelial ovarian carcinoma (EOC) cells. We first examined the correlation between expression levels of DPPIV and sensitivity to paclitaxel in various EOC cell lines. Subsequently, to clarify the cellular functions of DPPIV, we investigated the role of this molecule in the sensitivity of EOC to...

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Source: Women's Health Weekly (2010-03-25)

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