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University of California - San Francisco

Benefits of osteoporosis treatments outweigh possible risk of rare femoral fractures

Published in Women's Health Weekly, April 8th, 2010

The occurrence of an unusual type of fracture of the femur, or the thigh bone, is very low in patients with osteoporosis, including those treated with the drug family known as bisphosphonates, according to a new study led by a team of UCSF epidemiologists.

While these unusual femur fractures have been reported in case series studies in patients, particularly in those taking bisphosphonates, this UCSF study is the first to examine their occurrence systematically using data from randomized trials, the most rigorous type of study design. The study combined data from three bisphosphonate trials that involved more than 14,000 patients.

The new findings...

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